Podcast
Dr Javed Butler: Vericiguat: RRR vs. ARR
Why is considering ARR so important while we look at clinical trial data
Dr. Javed Butler highlights the importance of understanding absolute risk reduction (ARR) for patients with worsening heart failure, as it directly reflects the therapy's impact on individual outcomes. He explains the interplay between relative risk reduction (RRR) and ARR, noting that the higher the absolute risk at baseline, the higher that relative risk will translate into an absolute risk reduction. This emphasizes the need for clinicians to apply nuanced judgment in interpreting trial data and individualizing care.
