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Podcast

Dr Javed Butler: Vericiguat: RRR vs. ARR

Why is considering ARR so important while we look at clinical trial data

Dr. Javed Butler highlights the importance of understanding absolute risk reduction (ARR) for patients with worsening heart failure, as it directly reflects the therapy's impact on individual outcomes. He explains the interplay between relative risk reduction (RRR) and ARR, noting that the higher the absolute risk at baseline, the higher that relative risk will translate into an absolute risk reduction. This emphasizes the need for clinicians to apply nuanced judgment in interpreting trial data and individualizing care.

Our speakers

  • MD, MPH, MBA, Baylor Scott and White Health.

    Dr. Javed Butler is a prominent figure in cardiovascular medicine, especially known for his work on heart failure. Based in Dallas, Texas, he holds leadership positions at Baylor Scott & White, including the Maxwell A. and Gayle H. Clampitt Endowed Chair, president, and chief research executive at the Research Institute, and senior vice president at the Health system. His expertise is recognized by his fellowships in several prestigious organizations, such as the Heart Failure Society of America, the European Society of Cardiology, the American College of Cardiology, and the American Heart Association.

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