Anna

The choices you make today can impact Anna’s future

Anna today: 50 years old

  • Full-time teacher and mother of 2 teenagers
  • Living with T2D and CKD for 6 years

 

Kidney profile

  • Albuminuria: 50 mg/g
    (+12 mg/g in the past year)
  • eGFR: 59 mL/min/1.73 m2
    (-5 mL/min/1.73 m2 in the past year)

 

CV profile

  • Family history of CV disease

 

Current medications:

  • Statins
  • Maximum tolerated dose of an ACEi
  • T2D medications* (HbA1c: 7.7%)

Anna in the future

  • Working only part time
  • Less active family life due to health concerns
  • Increased doses for both dyslipidemia and T2D medications

 

Kidney profile

  • Albuminuria: 310 mg/g
  • eGFR: 42 mL/min/1.73 m2

 

CV profile

  • Coronary artery disease
  • Symptomatic HFpEF
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Patients with CKD are at increased risk for CV events

Without additional intervention, Anna’s risk will grow

Increased albuminuria is associated with greater CV and renal risk
 

Risk of CV mortality or end-stage renal disease in patients with T2D

Graph 1
Adapted from Fox et al. 2012
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Take action now to help prevent further CV and renal damage

Brian's profile picture

The choices you make today can impact Brian’s future

Brian today: 50 years old

  • Newly retired, but busy grandfather of 2
  • Living with T2D and CKD for 10 years
  • Had an NSTEMI 3 years ago

 

Kidney profile

  • Albuminuria: 50 mg/g
    (+12 mg/g in the past year)
  • eGFR: 59 mL/min/1.73 m2
    (-5 mL/min/1.73 m2 in the past year)

 

Current medications:

  • Statins
  • Aspirin
  • Beta blocker
  • T2D medications* (HbA1c: 7.7%)
  • Calcium channel blocker
  • Diuretic
  • Maximum tolerated dose of an ACEi

Brian in the future

  • Retired; less active family life due to health concerns
  • Increased doses for both dyslipidemia and T2D medications

 

Kidney profile

  • Albuminuria: 360 mg/g
  • eGFR: 38 mL/min/1.73 m2

 

CV profile

  • Has symptomatic HFpEF
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Patients with CKD are at increased risk for CV events

Without additional intervention, Brian’s risk will grow

Increased albuminuria is associated with greater CV and renal risk
 

Risk of CV mortality or end-stage renal disease in patients with T2D

Graph 2
Adapted from Fox et al. 2012
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Take action now to help prevent further CV and renal damage

Maggie's profile picture

The choices you make today can impact Maggie’s future

Maggie today: 60 years old

  • Works full time as a teacher and is a grandmother with an active family life
  • Living with T2D and CKD for 8 years

 

Kidney profile

  • Albuminuria: 280 mg/g
    (+65 mg/g in the past year)
  • eGFR: 54 mL/min/1.73 m2
    (-10 mL/min/1.73 m2 in the past year)

 

Current medications:

  • Statins
  • Multiple T2D medications* (HbA1c: 7.7%)
  • Calcium channel blocker
  • Diuretic
  • Maximum tolerated dose of an ACEi

Maggie in the future

  • Working only part time
  • Less active family life due to health concerns

 

Kidney profile

  • Albuminuria: 780 mg/g
  • eGFR: 40 mL/min/1.73 m2

 

CV risk factors

  • Diagnosed with HFpEF

 

Medication changes:

  • Increased doses for both dyslipidemia
    and T2D medications
Callout gold icon

Patients with CKD are at increased risk for both renal and CV events

Without additional intervention, Maggie’s risk will grow

Increased albuminuria is associated with greater CV and renal risk
 

Risk of CV mortality or end-stage renal disease in patients with T2D

Graph 3
Adapted from Fox et al. 2012
Callout gold icon

Take action now to help prevent further CV and renal damage